Music is a vital and lively part of the curriculum at Sancta Maria College. As well as an exciting classroom programme a number of  itinerant teachers come into school each week to offer specialist instrumental tuition in many instruments including Guitar, Drums, Percussion, Voice, Strings, Brass and Woodwind.

Co-curricular groups offered include: Jazz Band, Choir, Orchestra, String Ensemble, and Concert Band. These are open to all students attending Sancta Maria College. Also selected students play in the school show every second year.

Co-curricular groups perform at assemblies, prize giving, community concerts and regional competitions for a wide range of music from rock and jazz to classical and vocal.